Clavamox Is a Formulation Comprised of the Broad-spectrum Antibiotic Amoxicillin Trihydrate and the Β-lactamase Inhibitor Clavulanate Potassium (The Potassium Salt of Clavulanic Acid). Each Unreconstituted Bottle Contains 750 mg of Amoxicillin and 187.5 mg of Clavulanic Acid.
Uses
Clavamox drops are indicated for the treatment of:
Dogs:
Skin and Soft Tissue Infections such as wounds, abscesses, cellulitis, superficial/juvenile and deep pyoderma due to susceptible strains of the following bacteria:
- β-lactamase producing Staphylococcus aureus
- non-β-lactamase producing Staphylococcus aureus
- Staphylococcus spp., Streptococcus spp., and E. coli
Urinary Tract Infections (cystitis) due to susceptible organisms.
Gingivitis associated with periodontal infections due to susceptible strains of aerobic and anaerobic bacteria.
Cats:
Skin and Soft Tissue Infections such as wounds, abscesses, and cellulitis/dermatitis due to susceptible strains of the following bacteria:
- β-lactamase producing Staphylococcus aureus
- non-β-lactamase producing Staphylococcus aureus
- Staphylococcus spp., Streptococcus spp., E. coli, and Pasteurella spp.
Urinary Tract Infections (cystitis) due to susceptible organisms.
Therapy may be initiated with Clavamox prior to obtaining results from bacteriological and susceptibility studies. A culture should be obtained prior to treatment to determine susceptibility of the micro-organisms to Clavamox. Following determination of susceptibility results and clinical response to medication, therapy may be reevaluated.
Dosage & Administration
Dogs:
The recommended oral dosage of amoxicillin/clavulanic acid per kg of body weight is 12.5 mg twice daily for skin and soft tissue and urinary tract infections, and 13.75 mg twice daily for gingivitis.
Skin and soft tissue infections such as abscesses, cellulitis, wounds, and superficial/juvenile pyoderma should be treated for 5 to 7 days. Gingivitis should be treated for 7 to 10 days. Continue administration for 48 hours after all signs have subsided. If no response is seen after 5 days of treatment, therapy should be discontinued and the case reevaluated. Deep pyoderma may require treatment for 21 days. Urinary tract infections may require treatment for 10 to 14 days or longer. The maximum duration of treatment should not exceed 30 days.
Cats:
The recommended oral dosage is 62.5 mg of amoxicillin/clavulanic acid (1 mL) per animal twice daily.
Skin and soft tissue infections such as abscesses and cellulitis/dermatitis should be treated for 5 to 7 days. Continue administration for 48 hours after all signs have subsided. If no response is seen after 3 days of treatment, therapy should be discontinued and the case reevaluated. Urinary tract infections may require treatment for 10 to 14 days or longer. The maximum duration of treatment should not exceed 30 days.
Contraindications & Warnings
Contraindications:
The use of this drug is contraindicated in animals with a history of an allergic reaction to any of the penicillins or cephalosporins.
Warnings:
Keep out of reach of children.
Cautions:
Do not use in animals maintained for breeding purposes as safety has not been established. In case of anaphylaxis, administer epinephrine.
Pharmaceutical Precautions
Store unreconstituted product at a temperature between 15 and 25°C.
